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Athersys Inc.

Feeding response to ghrelin agonist and antagonist investigated

Published in Fitness and Wellness Business Week, February 9th, 2005

Scientists examine the feeding response to a ghrelin agonist and antagonist in lean and obese Zucker rats in a recent issue of the journal Life Sciences.

According to a study from France and the United States, "Ghrelin is a new orexigenic and adipogenic peptide primarily produced by the stomach and the hypothalamus. In the present experiment, we determined the circulating ghrelin levels in 60-week old fa/fa Zucker rats with a well-established obesity (n=12) and in their lean (FA/FA) counterparts (n=12). We also tested the feeding response of both groups to intra-peritoneal (ip) injection of ghrelin agonist and antagonist."

"Obese rats ate...

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