Aarhus University Hospital
Monocyte chemoattractant protein-1 higher in visceral than subcutaneous fat
Published in Fitness and Wellness Business Week, June 8th, 2005
According to recent research from Denmark, "Human adipose tissue (AT) cultures, isolated adipocytes, and stromal-vascular cells were used to investigate the relationship among AT-resident macrophages, MCP-1, and adiposity and the regulation of MCP-1. MCP-1 production is higher in stromal-vascular cells vs adipocytes (p<0.01) and correlates with macrophage markers in both AT compartments (p<0.05). MCP-1 release is higher in obese subjects (p<0.05) and in VAT (p<0.01), but after adjusting for AT-resident macrophages, the differences disappear."
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