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Karolinska Institute

Gallbladder bile changes in obese subjects after surgery examined

Published in Fitness and Wellness Business Week, August 3rd, 2005

Scientists examine changes in gallbladder bile composition and crystal detection time in morbidly obese subjects after bariatric surgery in a recent issue of Hepatology.

"The aim of the present study was to elucidate the mechanisms of development of cholesterol crystals and gallstones during weight reduction in obese subjects. Twenty-five morbidly obese, gallstone-free subjects underwent vertical-banded gastroplasty. Gallbladder bile was collected at the time of the operation via needle aspiration and 1.1-7.3 months after the operation via ultrasound-guided transhepatic puncture of the gallbladder. The mean weight loss was 17 kg. Two patients developed gallstones...

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