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Apoptosis Therapy
Studies from Wonkwang University, College of Pharmacy describe new findings in apoptosis therapy
May 21st, 2008
A report, 'Fatty acids ameliorate doxorubicin-induced intracellular ca2+ increase and apoptosis in rat cardiomyocytes,' is newly published data in Biological and Pharmaceutical Bulletin. "Doxorubicin (Dox) is a highly effective anticancer drug but exhibits cumulative dose-dependent cardiomyopathy. In this study, we investigated effects of Magnolia seed extract (MagS) on the Dox-induced cardiotoxicity," researchers in Korea report. "The results showed that MagS significantly reduces doxorubicin (Dox)-induced increase in intracellular Ca2+ concentration ([Ca2+]i), generation of reactive oxygen species (ROS), and apoptosis in rat cardiomyocytes. Analyses of the...
Source: Fitness & Wellness Business Week (2008-05-21)
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