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Fitness & Wellness Business Week

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Enzyme Research



Investigators at Institute of Physiology zero in on enzyme research



July 2nd, 2008

New investigation results, 'Modification of respiratory-chain enzyme activities in brown adipose tissue mitochondria by idebenone (hydroxydecyl-ubiquinone),' are detailed in a study published in Journal of Bioenergetics and Biomembranes. "Idebenone (IDE), a synthetic analog of coenzyme Q, strongly activates glycerol phosphate (GP) oxidation in brown adipose tissue mitochondria. GP oxidase, GP cytochrome c oxidoreductase and GP dehydrogenase activities were all significantly stimulated by 13 mcM IDE," scientists in Czech Republic report.

"Substituted derivatives of IDE acetyl-and methoxyidebenone had similar activating effects. When succinate was used as...


Source: Fitness & Wellness Business Week (2008-07-02)

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