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Drug Resistance
New data from Catholic University, Department of Oncology illuminate research in drug resistance
August 20th, 2008
Fresh data on drug resistance are presented in the report 'Proteomic characterization of cytoskeletal and mitochondrial class III beta-tubulin.' "Class III beta-tubulin (TUBB3) has been discovered as a marker of drug resistance in human cancer. To get insights into the mechanisms by which this protein is involved in drug resistance, we analyzed TUBB3 in a panel of drug-sensitive and drug-resistant cell lines," scientists in Campobasso, Italy report. "We identified two main different isoforms of TUBB3 having a specific electrophoretic profile. We showed that the apparently higher molecular weight isoform is glycosylated and phosphorylated and it is localized in the...
Source: Fitness & Wellness Business Week (2008-08-20)
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