Adipose Tissue
Studies from University of Pennsylvania have provided new information about adipose tissue
Published in Fitness and Wellness Business Week, April 1st, 2009
According to recent research published in the journal Proceedings of the National Academy of Sciences of the United States of America, "Adipocyte differentiation is controlled by many transcription factors, but few known downstream targets of these factors are necessary for adipogenesis. Here we report that retinol saturase (RetSat), which is an enzyme implicated in the generation of dihydroretinoid metabolites, is induced during adipogenesis and is directly regulated by the transcription factor peroxisome proliferator activated receptor gamma ( PPAR gamma)."
"Ablation of RetSat dramatically inhibited adipogenesis but, surprisingly, this block was not overcome by...
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