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Fitness & Wellness Business Week

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Angiogenesis



Groningen University publishes research in angiogenesis



April 1st, 2009

According to recent research published in the Journal of Cardiovascular Pharmacology, "Myocardial infarction (MI)-induced remodeling is associated with disturbed myocardial perfusion through vascular changes, such as reduced capillary density and endothelial dysfunction. Heart rate reduction (HRR) initiated immediately after MI stimulates angiogenesis and attenuates left ventricular dysfunction."

"We aimed to investigate the effects of long-term HRR on cardiac angiogenesis and endothelial function in a rat model of post-MI heart failure. Rats received early or late ivabradine or metoprolol for 12 or 9 weeks, respectively, and compared with untreated MI and sham...


Source: Fitness & Wellness Business Week (2009-04-01)

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