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Environment and Toxicology

Research from University of Allahabad in environment and toxicology provides new insights

Published in Fitness and Wellness Business Week, January 20th, 2010

"In utero and lactational exposure to organophosphate dimethoate exerted toxic impact on the reproductive system of male mice. Pregnant mice were exposed to 4, 8, and 16 mg/kg of the pesticide, the sublethal doses (2.5, 5, and 10% of Lethal Dose(50) [LD50]), via gavaging from gestation day (GD) 6 to postnatal day (PND) 21," scientists in Allahabad, India report.

"The effects on the male reproductive system were evaluated at two stages: at prepubertal age (PND 22) and at the postpubertal age of PND 63. Gonadal inhibition was reflected in the significant reduction of weight and distinct histopathological alteration of testis and epididymis as well as in decreased sperm...

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