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Aphton Corporation

Results of phase II study of G17DT vaccine reported

Published in Food and Drug Law Weekly, June 25th, 2004

Aphton Corporation (APHT) announced that the results from a phase II dose-ranging study of G17DT vaccine in gastric carcinoma were published in the European Journal of Surgical Oncology.

The study showed that G17DT immunization was capable of raising functional antibodies to gastrin 17 in patients with gastric adenocarcinoma. Immunization was well tolerated with no evidence of autoimmune reaction or development of immunological tolerance by repeated immunization. A multicenter phase III trial is ongoing testing G17DT in combination with the chemotherapeutic gemcitabine for the treatment of patients with advanced pancreatic cancer.

The primary...

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