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Fujita Health University
Dermatitis-like symptoms seen in HR-1 hairless mice on low magnesium/zinc diet
September 24th, 2004
Researchers observed atopic dermatitis-like symptoms in HR-1 hairless mice fed a diet low in magnesium and zinc. "We aimed to develop an animal model for atopic dermatitis. HR-1 hairless mice fed a diet with reduced magnesium and zinc levels were compared with mice fed a standard diet. Skin dryness and wrinkle-like changes, scratching behavior, decreased skin water content, increased transepidermal water loss, and raised blood immunoglobulin E levels were seen in the group receiving the reduced magnesium and zinc diet compared with control mice," researchers in Japan reported. "There were no significant differences in body weight or the weight of the...
Source: Food & Drug Law Weekly (2004-09-24)
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