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AstraZeneca LP
Ximelagatran does not interact with digoxin
September 24th, 2004
There is no significant pharmacological interaction between ximelagatran and digoxin. According to recent research from the United States, the "interaction potential of digoxin and ximelagatran, an oral direct thrombin inhibitor being developed for the prevention and treatment of thromboembolic disease," was evaluated in a "randomized, double-blind, 2-way crossover study." "On two separate occasions, healthy female and male volunteers (n=16) received ximelagatran 36 mg or placebo twice daily for 8 days separated by a 4- to 14-day washout period," explained T.C. Sarich and coauthors at AstraZeneca LP. "All volunteers received a single oral dose of...
Source: Food & Drug Law Weekly (2004-09-24)
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