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University of Virginia, Charlottesville

Only adverse effects of spironolactone in pediatrics was alteration of potassium

Published in Food and Drug Law Weekly, June 24th, 2005

A recent report describes clinical experience with spironolactone in pediatrics.

"In 2003, the Food and Drug Administration placed spironolactone on its list of drugs needing pediatric studies. To describe the use of spironolactone in a large group of children and evaluate its safety, focusing on its effects on potassium, a prospective observational study was conducted," scientists in the United States report.

M.L. Buck of the University of Virginia Health Systems explained, "Patient demographic information was collected, as well as dosing regimens, use of other medications, and potassium concentrations. Patients were grouped by diagnosis....

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