University of Texas, U.S.
Two susceptibility test methods to determine daptomycin MICs are compared
Published in Food and Drug Law Weekly, August 18th, 2006
According to their report, "Daptomycin is a lipopeptide antibiotic with activity against several important Gram-positive bacterial pathogens, including drug-resistant staphylococci and enterococci. Because the mechanism of action of daptomycin is calcium-dependent depolarization of the cell membrane, susceptibility testing requires medium supplemented with a physiological level of calcium. This study assessed two Food and Drug Administration-cleared commercial test...
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