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Gastroenterology Week

Susan Hasty, Publisher

Table of Contents . . . January 12th, 2004

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Gastroenterology Week | Other Publications

Gastroenterology - Survivin halts gastric cancer tumorigenicity and angiogenesis

Antimicrobial Antibodies - Activated gamma delta T cells go to lymph nodes; increase antibody production

Aphthous Stomatitis - Oral ulceration may indicate Behcet disease, inflammatory bowel syndrome

Appendicitis - Having appendix removed by laparoscopy means faster recovery

Barrett Esophagus - CPMP positive opinion issued in Europe for Photobarr

Bile Duct Tumors - Investigational new drug application filed for XL119

Biliary Cirrhosis - Primary biliary cirrhosis research at Mount Sinai advances due to trust, trials

Bone Growth - Animal model shows Korean herbal medicine promotes chondrocyte, bone growth

Cancer Incidence - Greenlandic Inuit have increased incidences of several cancers

Clostridium - Cholera toxin protects against Clostridium difficile toxin A

Collaborations - Oncology deal signed for development of orally active MEK inhibitor

Rotavirus - Cytokines act as mediators for or effectors against rotavirus disease

Collaborations - Pharmaceutical company signs agreement for probiotics development

Colon Tumors - Sphingolipids may be an alternative to conventional drugs

Colorectal Cancer - Irinotecan is effective second-line therapy for 5-FU resistant colorectal cancer

Computer-aided Diagnostics - Company reports FDA approvals, provides progress report

Crohn Disease - Company reports expanded reimbursement coverage for capsule endoscopy

Cystic Fibrosis - Milestone earned for development of malabsorption treatment

Environmental Testing - Immunomagnetic-based method detects Cryptosporidium, Giardia oocysts

Ephedra - FDA plans to prohibit sales of diet supplements containing ephedra

Food Technology - Opsonophagocytic assay may be a useful test for safe enterococcal strains

Gastric Cancer - BRAF mutations do not seem to be involved in gastric cancer development

Gastroenterology -  Helicobacter pylori influences angiogenesis and gastric cancer invasion

Gastroenterology - TNF-alpha may play an early role in the malignant transformation of liver cells

Glomerular Disease - Renal biopsy histology does not correlate highly with most clinical syndromes

Glomerulonephritis - Balance of activator, inhibitor Fc gamma receptors may influence kidney disease

Heat Shock Proteins - Neuroprotection due to HSP induction may occur with geranylgeranylacetone

Helicobacter Pylori -  H. pylori CagA inhibits B cell p53-induced apoptosis; triggers MALT lymphoma

Helicobacter Pylori - Company announces new rapid test for stomach ulcers

Hemolytic-Uremic Syndrome - Stx-liposome conjugates show promise as vaccine candidates

Immunology - Microwave energy dose affects immunoreactivity of gliadin and wheat flour

Inflammatory Bowel Disease - A pair of discoveries helps unravel complex genetics of IBS

Gastrointestinal Hemorrhage - Embolization highly effective, minimally invasive to control bleeding

Kidney Cancer - Primary renal synovial sarcoma is a spindle-cell tumor with SYT-SSX gene fusion

Kidney Diseases - Diagnosis of different paraproteinemias requires extensive renal histology

Kidney Transplant - Acute kidney rejection is lower with basiliximab, independent of cyclosporine

Liver Transplantation - Recent insights on the mechanisms of liver preconditioning evaluated

Lung Cancer - Cancer drug development status reported

Market Forecast - Report: G protein-coupled receptors have significant potential

Obesity Therapy - Nutrient selected for study of gastric bypass surgery patients

Pancreatic Cancer - Butyrate can inhibit pancreatic cancer metastasis by inhibiting P4 integrin

Patents - European regulatory authorities revoke patent related to Cellegesic

Periodontal Disease - Subgingival Treponema glycolipids can inhibit TLR, monocyte activation

Giardia Lamblia - Real-time PCR is at least as effective as antigen assay to detect G. lamblia

Personnel - Alex Franzusoff, PhD, named VP of research

Systemic Lupus Erythematosus - Lupus nephritis may occur with crystal structures made of immunoglobulins

Transplant Medicine - Complement deposition may soon be blockable; to stop kidney pathology, rejection

Transplant Medicine - Late rejection may still be due to antibodies; diagnostics, cures are needed

Transplant Medicine - Pediatric renal graft loss linked to non-adherence, teenage, mental illness

Transplant Medicine - Renal function improves in pediatric liver transplant by switch in monitoring

Transplant Medicine - Targeting of chemokine receptors may help stop allograft rejection

Urinary Tract Infection -  Staphylococcus sciuri group may be an infrequent cause of UTI

Panniculitis - Sclerosing mesenteritis can be diagnosed, followed up by 3-dimensional CT

Adverse Drug Effects - Liver transplant patients with renal dysfunction from CNI may improve with MMF

Allergy Medicine - Different laboratories find little variability between ELISAs for egg in food

Allergy Medicine - IgA in blood products causes anaphylaxis following transfusion in those with anti-IgA

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