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Gastroenterology Week

Susan Hasty, Publisher

Table of Contents . . . September 6th, 2004

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Gastroenterology Week | Other Publications

Diagnostic Imaging - Imaging studies enhance the diagnosis and management of infected livers

Diarrhea - Hospital-acquired diarrhea increases medical/economic load in pediatric units

Diet and Nutrition - Black beans play role in etiology of several diseases in Guatemala

Gastroenterology Vaccine - Activity of E. coli phages have implications for phage therapy

Helicobacter Vaccine - Plasmid encoding H. pylori urease induces specific antibody response

Viral Genomics - Sapovirus isolates from outbreaks and acute gastroenteritis classified

Abdominal Angina - Utility of multi-detector row CT angiography reviewed

Adverse Drug Events - Cancer drug Avastin use increases risk of stroke, heart attack

Amebiasis -  E. histolytica genomic response to trophozoite collagen binding determined

Anemia - Aranesp receives positive regulatory opinion for extended dosing in Europe

Anthrax - Dermatological aspects of anthrax reviewed

Bacterial Genomics -  S. dysenteriae 1 isolates derived from clone from single phage-integration event

Business and Finance - Pharmaceutical company reports second quarter, clinical development results

Cancer Vaccine - Pemetrexed (ALIMTA) is novel multitargeted antineoplastic agent

Cholera Vaccine - Biosafety aspects of live oral Vibrio cholerae vaccine strain examined

Chronic Liver Disease - Disease severity differs in North American and United Kingdom liver recipients

Chronic Liver Disease - Non-invasive elastometry is a valuable tool for staging liver fibrosis

Colon Cancer - Are physicians over-performing colonoscopy?

Colon Cancer - Hyaluronan pairs with CD44 to encourage colon carcinoma cell invasion

Colon Cancer - New guideline does not recommend chemotherapy for stage II colon cancer

Colorectal Cancer - Stool-based DNA testing reviewed

Cystic Fibrosis - Acidic duodenal pH alters pancreatic gene expression in mice

Cytomegalovirus - CMV prophylaxis following BMT has changed the natural history of the disease

Cytomegalovirus Infection - Prophylaxis with valganciclovir is effective in organ transplantation

Diabetes Therapy - Glibornuride protects against liver damage in experimental diabetes

Diabetic Nephropathy - Glycogen synthase defect not based on glycogen synthase kinase-3 alpha

Diabetic Nephropathy - Tamm-Horsfall protein decreased in patients with diabetes

Diabetic Nephropathy - Transforming growth factor blockade treats diabetes-related kidney disease

Diagnostics - Company launches VoLumen oral bowel marker for MDCT and PET/CT studies

Diagnostics - Full lab evaluation of patients needed to correctly diagnose chronic diarrhea

Diet and Nutrition - Resistant starch provides health benefits

Drug Delivery - Liposomal benznidazole has similar efficacy to standard formulation

Drug Development - Liposomal Cratylia mollis lectin has improved antitumor efficacy

Finance - GERD-focused company closes $12 million series B financing

Finance - Gastro-focused company reports Q2 net loss of $7.6M

Gastroenterology - Antiangiogenic agents are important adjuncts to conventional chemotherapy

Gastroenterology - Nonsulfated CCK58 has surprising physiological properties

Gastroentrology - Specialty pharmaceutical company gains settlement regarding patents

Gastrointestinal Stromal Tumors - Glivec recommended as first line management for gastrointestinal stromal tumors

Genomics - Effective liver cell transduction relies on viral second-strand DNA synthesis

Helicobacter Vaccine - Regulatory T cells suppress H. pylori-reactive immunopathological T cells

Hepatocellular Carcinoma - Raf-1 activation linked to pathogenesis

Hepatology - Proapoptotic effects of SAMe in HepG2 cells elucidated

Immunology - Interferon-gamma signals slow progression in hepatitis C-infected patients

Immunosuppression - Rapid steroid withdrawal is appropriate for HCV-positive kidney recipients

Infectious Disease - Greater risk of systemic infection with epidemic L. monocytogenes strains

Inflammatory Bowel Disease - Promotion of Entocort, a locally acting glucocorticosteroid, begins in Germany

Liver Transplantation - Isolated small intestinal segments support transplanted liver fragments

Liver Transplantation - Liver transplant recipients face graft rejection with interferon-based therapy

Medical Devices - U.S. FDA approves rabbit monoclonal antibody kit for GI tumor diagnosis

Metastasis - Radioimmunotherapy and antiangiogenic therapy extend survival in cancer models

Mutagenesis - Alkaloid riddelliine induces mutations in liver cII gene of Big Blue rats

Obesity Pathogenesis - Ghrelin expression reduced in stomachs of obese mice

Obesity Pathogenesis - Ghrelin plays role in obesity development outside of leptin signaling

Oncogenesis - Hepatitis B virus x protein halts apolipoprotein B production in liver cells

Pancreatic Cancer - Genomic DNA-chip hybridization used to identify novel gene amplifications

Pancreatic Cancer - Triplex-forming oligonucleotide curtails the oncogene Ki-ras

Pediatrics - dGK gene analysis should be performed on infants with cirrhosis

Personnel - GU/GI-focused company names Jan H. Egberts, MD, as chief operating officer

Personnel - Powerlink System developer names Robert J. Krist CFO

Primary Sclerosing Cholangitis - MRC more cost-effective than ERCP for diagnosis

Renal Allograft - Malignancy reported in sirolimus-treated renal transplant recipients

Renal Cell Carcinoma - Bcl-2 antisense nucleotide sensitizes interferon-resistant renal cancer to Fas

Renal Disease - TGF-beta1-induced glomerulopathy in mice prevented by estrogen supplementation

Stem Cell Transplantation - Mesenchymal SCs help repair kidney and improve function in acute renal failure

Transplant Medicine - Interferon may lead to graft loss in liver transplant recipients

Transplant Medicine - Race affects the outcomes of patients awaiting liver transplantations

Ulcerative Colitis - Enrollment continues in retreatment phase of Nuvion trial

Ulcerative Colitis - Friendly bacteria offers hope for ulcerative colitis patients

Ulcerative Colitis - Researchers find that expression of COX-2, NOS2 may play role in colitis

Urology - Histone deacetylase inhibitors improve the transfection of bladder cancer cells

Vaccine Delivery - Oral delivery system containing A/Panama influenza hemagglutinin optimized

Viral Proteomics - Hepatitis E virus protein ushers liver-specific precursor protein from cells

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