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Irritable Bowel Syndrome

Studies find sex-based differences in gastrointestinal pain

Published in Gastroenterology Week, November 22nd, 2004

Gastrointestinal pain due to irritable bowel syndrome is experienced differently in men than women.

"Recent interest has focused on sex-related differences in irritable bowel syndrome (IBS) physiology and treatment responsiveness to novel pharmacologic therapies," said E.A. Mayer and colleagues, University of California, Los Angeles.

"Similar to a variety of other chronic pain conditions and certain affective disorders, IBS is more prevalent amongst women, both in population-based studies as well as in clinic-based surveys. Non-painful gastrointestinal symptoms, constipation, and somatic discomfort are more commonly reported by female IBS patients,"...

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