Pancreatic Cancer
Pancreatic carcinoma cells susceptible to Ad.mda-7-induced apoptosis
Published in Gastroenterology Week, March 28th, 2005
"Pancreatic cancer is exceptionally aggressive with no long-term effective therapy. Current interventional approaches, including surgery, radiation and/or chemotherapy, have done little to quell the mortality associated with this malignancy," scientists writing in the journal Oncogene report.
"Subtraction hybridization identified a cancer-specific apoptosis-inducing cytokine gene, melanoma differentiation associated gene-7/interleukin-24 (mda-7/IL-24), with a broad range of selective antitumor activity in diverse cancers both in vitro and in...
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