Lymphoma
CXCR3-positive B cells attracted by MIG might belong to the lymphoma clone
Published in Gastroenterology Week, June 13th, 2005
"Chemokine receptors mediate the migration of lymphocytes through binding of their ligands. CXCR3 is expressed in Th1 T cells; however, CXCR3 was recently reported in B-cell mucosa-associated lymphoid tissue (MALT)-type lymphoma and splenic marginal zone lymphoma," investigators in Japan reported.
"To investigate whether CXCR3-positive B lymphocytes in peripheral blood (PB) migrate to MALT and spleen, and whether the lymphoma clone is present in PB, we studied 16 cases of MALT lymphoma," explained H. Suefuji and colleagues, Fukuoka...
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