Cholera

Positive preliminary results from clinical trial of cholera vaccine reported

Published in Gastroenterology Week, August 22nd, 2005

AVANT Immunotherapeutics, Inc., (AVAN) announced a breakthrough in the control of cholera with positive preliminary results from a phase II clinical trial of CholeraGarde in infants and children.

The researchers found the single dose, oral vaccine to be well tolerated and highly immunogenic, with 77% of children aged 9 months to 5 years generating protective immune responses. The ability to induce protective immune responses in children under age two would allow the introduction of the vaccine into the routine pediatric immunization calendar in endemic regions.

There are currently no licensed cholera vaccines indicated for use in children under age...

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Source: Gastroenterology Week (2005-08-22)

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