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Daily marijuana use exacerbates chronic hepatitis C-related liver fibrosis

Published in Gastroenterology Week, August 22nd, 2005

Daily marijuana uses exacerbates chronic hepatitis C-related liver fibrosis.

"Cannabinoids present in Cannabis sativa (marijuana) exert biological effects via cannabinoid receptors CB1 and CB2. We recently demonstrated that CB1 and CB2 receptors regulate progression of experimental liver fibrosis," scientists writing in the journal Hepatology report.

"We therefore investigated the impact of cannabis smoking on fibrosis progression rate in patients with chronic hepatitis C (CHC). Two hundred seventy consecutive untreated patients with CHC of known duration undergoing liver biopsy were studied. Demographic, epidemiological, metabolic, and...

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