Hepatitis C Virus

Donor origin affects hepatitis C virus kinetics in recipients of liver grafts

Published in Gastroenterology Week, January 30th, 2006

Recent research from the United States has chronicled accelerated hepatitis C virus (HCV) kinetics but similar survival rates in recipients of liver grafts from living versus deceased donors.

"This study tested the hypothesis that HCV RNA and core antigen levels rise more rapidly after liver transplantation (LT) in recipients of grafts from living donors (LD) versus deceased donors (DD)," wrote T.D. Schiano and colleagues, Mount Sinai School of Medicine.

"Eleven consecutive LD and 15 DD recipients were followed prospectively. Before LT, median HCV RNA levels were similar: 5.42 (LDLT) and 5.07 (DDLT) log¹⁰ IU/mL (p=NS). During the first 7...

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Source: Gastroenterology Week (2006-01-30)

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