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Gastroenterology Week

Susan Hasty, Publisher

Table of Contents . . . March 6th, 2006

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Gastroenterology Week | Other Publications

Inflammatory Bowel Disease - Budesonide is effective for treatment of inflammatory bowel disease

Liver Diseases - Nutrition alters hepatocellular damage in NASH and alcoholic liver disease

Pancreas - Pancreatic leak incidence reduced by neoadjuvant chemoradiotherapy

Rotavirus Vaccine - Review examines risks and benefits of rotavirus vaccines in Latin America

Salmonella Outbreaks - Source of S. enteritidis phage type 36 outbreak in Austria not identified

Adrenocortical Cancer - Therapeutic strategies for treating adrenocortical carcinoma discussed

Adverse Drug Reaction - Reflux treatment linked to life-threatening bowel infection in premature infants

Alcoholic Hepatitis - ADAMTS13 may contribute to multiorgan failure in alcoholic hepatitis

Alcoholic Hepatitis - Severe alcoholic hepatitis ascertained in Japan

Antibiotic-Resistant Salmonella -  S. typhimurium DT104 epidemic strains isolated from animals and feed in Poland

Apoptosis - Reports advance knowledge in apoptosis research

Bioreactor - Model accurately predicts dissolved oxygen consumption within a hepatic fiber bioreactor

Breast Cancer - Researchers publish new studies and findings in the area of breast cancer

Cancer Diagnostics - Colon dissection approach deemed advantageous for evaluating CT colonography

Cancer Diagnostics - Fine-needle aspirates of hepatocellular cancer could be misclassified as adenocarcinoma

Cancer Diagnostics - Residual tumor after radiofrequency ablation of liver metastasis detected with dual-modality PET/CT

Cancer Gene Therapy - Pancreatic carcinoma can be treated by adenoviral mediated gene transfer of vasostatin

Cancer Therapy - Abbott has selected two additional cancer targets for development, genomics firm reports

Cancer Therapy - Antitumor benzothiazoles showed inhibitory activity against cancer cell lines

Cancer Therapy - Cancer cell ablation occurs using irreversible electroporation

Cancer Therapy - CoFactor phase IIb trial surpasses 50% enrollment milestone

Cancer Therapy - Combination sorafenib and gemcitabine stabilizes disease in advanced solid tumors

Cancer Therapy - Irofulven cytotoxicity characterized in human cancer cells

Cancer Therapy - Oleanolic derivative compound protects against liver cancer

Carcinogenesis - Deregulation in human rectal carcinomas depends on aneuploidy

Cardiovascular Disease - Study compared B-type natriuretic peptides for assessing cardiac function in ischemic heart disease

Cholecystectomy - Bulging midriff roughly doubles women's chances of gallstone surgery

Chronic Hepatitis C - Interferon-ribavirin combination therapy is limited for older patients with chronic hepatitis C

Chronic Myeloid Leukemia - Test launched to monitor Gleevec resistance

Cirrhosis - Acute renal failure predicted in patients with advanced liver cirrhosis

Cirrhosis - rhHGF-activator stimulates cirrhotic liver regeneration

Clinical Trials - Antibiotic candidate proven effective against Clostridium Difficile associated diarrhea

Clinical Trials - Health Canada issues "No Objection" letter for cancer phase I clinical trial

Collaborations - Pharma company extends R&D alliance with AstraZeneca for GI drug development

Colon Cancer - Cell cycle arrest and apoptosis may be equipotent mechanisms in colon cancer

Colon Cancer - Effect of indomethacin on E-cadherin and beta-catenin expression in colon cancer studied

Colon Cancer - FOLFOX4 regimen is safe, effective for elderly colon cancer patients

Colon Cancer - Induction of oxidative metabolism by mitochondrial frataxin may inhibit cancer growth

Colon Cancer - Lessons from developing and running clinical database for colorectal cancer discussed

Colon Cancer - New findings in the area of colon cancer described

Colon Cancer - Oral uracil/ftorafur plus leucovorin treated metastatic colorectal cancer

Colon Cancer - Recent findings in colon cancer described

Colorectal Cancer - Lifestyle characteristics among patients in Norwegian colorectal cancer screening trial analyzed

Colorectal Cancer - Long-term outcomes of laparoscopic surgery for colorectal cancer reviewed

Colorectal Cancer - PRL and survival of CRC patients affected by tumor location and radiotherapy

Colorectal Cancer - Patients operated for colorectal cancer linked to high risk of recurrence

Complementary & Alternative Medicine - Curcumin uses transcription factor Egr-1 to suppress epidermal growth factor receptor expression

Crohn Disease - Bovine paratuberculosis may not be a cause of Crohn disease

Cryptococcus Pathogenesis -  Cryptococcus gattii NIH444 is preferred strain for molecular pathogenesis study

Cryptosporidiosis Outbreaks - Cryptosporidiosis outbreak associated with swimming pool exposure in water park

Diabetes Therapy - LAGB prevents diabetes and arterial hypertension and induces their remission in morbid obesity

Diagnostics -  Vibrio cholerae repeat sequences-PCR rapid and discriminatory for surveillance

Diagnostics - Alcoholic hepatitis differentiated from non-alcoholic steatohepatitis

Diagnostics - An rK39 antigen-based dipstick provides optimal field diagnosis of visceral leishmaniasis

Diagnostics - Ingested video capsule compares to endoscopy in detecting esophageal varices, studies show

Diagnostics - Initial combined use of noninvasive tests useful in diagnosing IBD in children

Diagnostics - Institut Pasteur cholera dipstick provides accurate results despite low user skill

Diagnostics - New research in the area of diagnostics detailed

Diagnostics - PDL gets distribution rights for prion disease test

Diagnostics - Vascular endothelial growth factor messenger RNA may predict liver metastases

Diet & Nutrition - AICAR, an AMPK activator, has protective effects on alcohol-induced fatty liver in rats

Diet & Nutrition - Calcium plus vitamin D may contribute to reduced polyp formation

Diet & Nutrition - Low-fat diet benefits for women less than expected, Stanford researcher says

Disease Associations - Breast cancer risk elevated in first-degree relatives of Crohn disease patients

Disease Associations - Choice of age cut-off for dyspepsia may decrease endoscopy workload

Disease Associations - Diabetes is linked with the development and progression of non-alcoholic steatohepatitis

Disease Associations - Insulin resistance is associated with steatosis in chronic hepatitis C

Disease Associations - Intraductal papillary mucinous neoplasms linked to extrapancreatic neoplasms

Drug Development - Biopharma firm seeks U.S. FDA approval for synthetic secretin product

Drug Development - Dasatinib may affect neoplasms associated with gain-of-function KIT mutations

Drug Development - Dual tyrosine kinase inhibitor GW572016 hampers colon cancer cells

Endocrinology - Researchers publish new studies and findings in the area of endocrinology

Epidemiology - Antagonistic interactions among marine bacteria impede V. cholerae proliferation

Escherichia Coli Outbreaks -  Escherichia coli O157 outbreak associated with fresh unpasteurized goat cheese

Finance - Biopharma company reports total third quarter revenue of $2,988,000

Finance - Biotech company provides update on 2005, reports revenues of $646,000

Finance - Pharmaceutical company secures $75 million committed equity financing facility

Finance - Protein-based diagnostic products developer announces annual revenues of $2,818,000

Food Safety - Methods are compared for detecting Escherichia coli in orange juice

Gallbladder Cancer - Changing patterns of gallbladder carcinoma in New Mexico analyzed

Gallbladder Carcinogenesis - Microsatellite instability plays only minor role in gallbladder carcinogenesis

Gastric Cancer - Biweekly irinotecan and cisplatin found effective in treating advanced gastric cancer

Gastric Cancer - Laparoscopy-assisted distal gastrectomy used to treat early gastric cancer

Gastroenterology - European filings of mesalazine compound for treating ulcerative colitis announced

Gastroenterology - GLP-2 stimulates glucagon secretion, raises lipid absorption, inhibits gastric acid secretion

Gastrointestinal Cancer - Endoscopic detection of early lower gastrointestinal cancer discussed

Gastrointestinal Stromal Tumors - Clinicopathological findings of gastrointestinal stromal tumors analyzed

Genetics & Genomics - DNA-focused diagnostics company to supply Children's Hospital with genetic test reagents

Genetics & Genomics - Gene expression patterns correlate with early progression to fibrosis in liver transplants

Hepatitis B Virus - Antioxidant supplementation may be warranted in acute or chronic hepatitis B

Hepatitis B Virus - Emtricitabine assisted in the treatment of chronic hepatitis B infection

Hepatitis B Virus - HBV-HCV co-infections are associated with a complex spectrum of virological profiles

Hepatitis C Virus - Anti-HCV effect is mechanistically linked to control of viral replication

Hepatitis C Virus - Anti-hepatitis C virus antibody quantified in patients with chronic hepatitis C

Hepatitis C Virus - HCV transmission from B-cells to hepatoma cells occurs by cell-to-cell contact

Hepatitis C Virus - Hepatitis C virus polyprotein translation is linked to polymerase function

Hepatitis C Virus - Intrahepatic cytokine expression is downregulated during HCV/HIV co-infection

Hepatitis C Virus - Mixed cryoglobulinemia is characterized by higher hepatitis C virus load

Hepatitis C Virus - Saliva nitric oxide levels are unchanged in HCV infected patients

Hepatocellular Cancer - CT features for distinguishing hepatocellular carcinoma from IDCC identified

Hepatocellular Cancer - Recent findings in hepatocellular cancer described

Hepatocellular Cancer - Subcellular localization of DLC2 determined

Hypertension - Serum GGT levels may predict hypertension among subjects with higher central fat distribution

Imaging - Assessment of myocardial perfusion adds value to conventional stress ECG

Imaging - Correlation observed between imaged and histological features of nonalcoholic steatohepatitis

Imaging - Method for specific dynamic and noninvasive labeling of beta cells in mice was developed

Inflammatory Bowel Disease - CD146 reflects vascular disturbances in patients with inflammatory bowel disease

Influenza - Medical alliance offers tips for avoiding stomach flu

Kaposi Sarcoma Risk Factors - Kaposi sarcoma risk higher in HIV/AIDS than in transplant recipients

Liver Cancer - Molecular fingerprints convey the angiogenic makeup of hepatocellular carcinoma

Liver Diseases - Nonalcoholic fatty liver disease is treatable by gastroplasty

Liver Diseases - Risk factors and ultrasound predict chronic hepatitis caused by nonalcoholic fatty liver disease

Lung Cancer - Aflatoxin B-1 altered expression of p53 in cytochrome P450-expressing lung cells

MALT Lymphoma - MALT lymphoma biology discussed

Medical Devices - Dexamethasone-eluting nitinol stent may inhibit pseudo-intimal hyperplasia in TIPS

Medical Devices - U.S. FDA approves computer-assisted colonoscopy system

Molecular Diagnostics - Data highlighting the role of molecular diagnostics presented at major HIV/AIDS meeting

Obesity Therapy - CNTF restores gallbladder contractility in leptin-resistant obese diabetic mice

Obesity Therapy - Findings describe new data in obesity therapy research

Obesity Therapy - GES induced tachygastria is mediated by an adrenergic pathway and inhibits antral motility

Obesity Therapy - Persistent decline of serum ghrelin and body weight was observed after total gastrectomy

Oncology - Researchers detail new studies and findings in the area of oncology

Outbreak Surveillance - Surveillance system using a helpline unlikely to detect local outbreaks

Ovarian Cancer - Long-acting octreotide used to treat bowel obstruction in ovarian cancer

Pain Management - Endoscopic stenting of pancreatic duct strictures provides pancreatitis pain relief

Pancreatic Cancer - Depression does not affect survival among patients with pancreatic cancer

Pancreatic Cancer - First strong evidence for anticipation in familial pancreatic cancer presented

Pancreatic Cancer - New findings in pancreatic cancer described

Pancreatic Cancer - New findings in the area of pancreatic cancer described

Pancreatic Cancer - Studies describe new findings in pancreatic cancer research

Personnel - Cancer diagnostics company taps Douglas Sweet to head marketing and sales

Philanthropy - Gift enables launch of public service campaign about Crohn disease and ulcerative colitis

Pituitary Gland - High-dose SST is safe for excluding secondary adrenal insufficiency

Product Licensing - Biotech company and Transgenomic enter exclusive European license and supply agreement

Product Licensing - Distribution and license agreement signed for Aloxi

Product Licensing - Pharma company acquires expanded worldwide rights to Ramoplanin

Product Licensing - Therapeutics company terminates exclusive license agreement with XenoTech

Prostate Cancer - Reports describe recent advances in prostate cancer research

Proteomics - New research in the area of proteomics detailed

Rotavirus Gastroenteritis - U.S. FDA approves Rotateq to prevent a leading cause of severe infant diarrhea

Shigella Outbreaks - Four Shigella waterborne outbreaks in Greece correspond to two epidemic waves

Steatohepatitis - JNK1 but not JNK2 promotes the development of steatohepatitis in mice

Steatohepatitis - Soluble TNF receptor is associated with non-alcoholic steatohepatitis

Surgical Technology - Endoscopic full-thickness gastric wall resection using flexible stapler shows promise

Surgical Technology - Laparoscopic ventral hernia repair appears to be a better method for obese patients

Transplant Medicine - Cyclosporine suppresses hepatitis C virus after liver transplantation

Vaccine Development - Phase I shows escalating doses of S. epidermidis and S. aureus vaccines are well-tolerated

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