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Gastroenterology Week

Susan Hasty, Publisher

Table of Contents . . . April 3rd, 2006

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Gastroenterology Week | Other Publications

Colon Cancer - Colonic lesions diagnosed by elastic scattering spectroscopy

Diagnostics - Crohn disease and intestinal TB diagnosis distinguished by colonoscopy and histopathology

Diet & Nutrition - High protein buckwheat flour prevents hypercholesterolemia, obesity, and gallstone formation

Drug Delivery - Chitosan does not increase drug availability in products when included in formulations

Gastric Cancer - Genetics, pathology, and clinical criteria of familial gastric cancer described

Acid Reflux - Gastroesophageal reflux disease requires rabeprazole for step-down therapy

Apoptosis - Hepatoma cell apoptosis is enhanced by interferon-alpha

Appendicitis - MRI rules out acute appendicitis in pregnancy

Arthritis - Rheumatoid arthritis can be distinguished from Sjogren syndrome

Autoimmune Diseases - In autoimmune hepatitis, P2X(7) receptors regulate NKT cells

Bone Marrow - Hepatocyte-bone marrow cell fusion is driven by immune-mediated hepatitis

Bone Marrow Transplantation - Transplanted bone marrow cells fail to adopt a pancreatic beta-cell fate

Business Update - DATATRAK awarded two phase III trials with Cosmo Technologies

Cancer Diagnostics - Likelihood of urban primary care physicians to recommend colonoscopy studied

Cancer Gene Therapy - Combination gene therapy is effective for pancreatic adenocarcinoma

Cancer Gene Therapy - Gastric cancer treatment aided by suicide gene therapy combined with hyperthermia

Cancer Gene Therapy - Methyltransferase depletion therapy mediates growth arrest and apoptosis

Cancer Gene Therapy - RNA interference inhibits the proliferation of pediatric hepatic tumors

Cancer Incidence - Frequency of additional cancers in patients with splenic marginal zone lymphoma assessed

Cancer Risk Factors - Cancer incidence studied in dry cleaning workers in Nordic countries

Cancer Therapy - Reports add new data to cancer therapy research

Cancer Therapy - Researchers' findings advance cancer therapy research

Carcinogenesis - Antitumor potential of beef conjugated linoleic acid isomers evaluated

Carcinogenesis - Hepatitis B and C viral interaction may have a role in hepatocellular carcinogenesis

Carcinogenesis - Hydrogen sulfide implicated as a genotoxic agent

Cleft Lip & Palate - Cleft lip/palate linked to CDH1/E-cadherin mutations in families with gastric cancer

Clinical Trials - C1-inhibitor concentrate relieves abdominal pain in angioedema patients, study shows

Clinical Trials - Novogen IBD drug phase I clinical trial shows promise

Clinical Trials - UCB submits biologics license application to U.S. FDA for new treatment in Crohn disease

Collaborations - Ace BioSciences, Nordic Vaccine unite to develop vaccines

Colon Cancer - Early, frequent colon cancer screenings encouraged for Crohn, ulcerative colitis patients

Colon Cancer - NetWellness premieres new colon cancer information site for consumers

Colorectal Cancer - Chemotherapy given directly to the liver improves survival for patients with colorectal cancer

Colorectal Cancer - Colorectal cancer can be treated with irinotecan, oxaliplatin and raltitrexed

Colorectal Cancer - Colorectal cancer rates do not appear affected by vitamin D and calcium supplements

Colorectal Cancer - Colorectal cancer treated by irinotecan, oxaliplatin, 5-fluorouracil and folinic acid

Colorectal Cancer - Endoscopic procedures and diagnoses not influenced by seasonal variations

Colorectal Cancer - Gilda's Club Worldwide launches art contest to illustrate colorectal cancer survival

Colorectal Cancer - Minimal preparation CT used to detect suspected colorectal cancer in elderly

Colorectal Cancer - Venous thromboembolic events linked to breast and colorectal carcinoma diagnoses

Dermatology - Nucryst Pharmaceuticals receives patent for proprietary nanocrystalline silver to treat acne

Diabetes Complications - HNF-1 beta mutations result in reduced insulin sensitivity of endogenous glucose production

Diabetes Control - Mosapride improves food intake without influencing glycemic control

Diabetes Epidemiology - Differences in 7B2 expression may explain variations in glucagon production and glucose tolerance

Diabetes Pathogenesis - Akt induces beta-cell proliferation by regulating cyclin D1, cyclin D2, and p21 levels and cdk4

Diabetes Pathogenesis - Decreased expression of SNARE influences impaired insulin secretion in type 2 diabetics

Diagnostics - Signet, Bayer sign agreement to do research on urinary trypsin inhibitor immunoassays

Diet & Nutrition -  Pleurotus citrinopileatus shows antihyperglycemic effect in diabetic mouse model

Diet & Nutrition - Lupin kernel fiber foods improved markers of healthy bowel and colon cancer risk

Drug Delivery - A mucoadhesive hydrogel may serve as a drug delivery device to the mucosal epithelium

Drug Delivery - NovaDel announces completion of clinical trials for Zensana oral spray for chemotherapy patients

Drug Development - American Pharmaceutical receives two tentative U.S. FDA approvals for Ondansetron

Endocrinology - Chronic hyperghrelinemia does not reduce orexigenic action of exogenous ghrelin

Enzymology - TNP-470 relies on MAPK/COX-2 signaling to block angiogenesis and liver fibrogenesis

Epidemiology - Anti-Yersinia antibody seroprevalence high in healthy Austrians

Epidemiology - Enteric disease risk and vaccination attitudes differs among rural Chinese

Esophageal Cancer - Chinese esophageal squamous cell carcinoma linked to aberrant RASSF1A gene

Esophageal Cancer - Esophageal cancer progression correlated with reduced PABPC1 expression

Food Safety - Grocery Manufacturers Association responds to National Uniformity for Food Act

Food Safety - Nymox NXC-4720 late-stage product targets Escherichia coli food contamination

Gastric Cancer - Gastric cancer response to chemotherapy not predicted by DNA methylation of CHFR

Gastric Cancer - Gastric cancer surgical outcomes compared between elderly and middle-aged patients

Gastric Cancer - Heparin encourages gastric cancer cell growth

Gastroenterology - Data advance knowledge in gastroenterology research

Gastroenterology - Data on Callisto's Guanilib to be presented at conference on digestive diseases

Gastroenterology - Gastro-esophageal reflux risk lowered by physical activity and fruit, raised by obesity and smoking

Gastroenterology - Intestinal barrier is modulated by miltefosine in the treatment of leishmaniasis

Gastrointestinal Tumors - Gastrointestinal tumors treated by capecitabine plus weekly oxaliplatin

HIV/AIDS & Hepatitis - Liver fibrosis is predicted in HIV/hepatitis C coinfections

Hepatitis & Hepatic Stenosis - Chronic hepatitis C is associated with virally induced hepatic stenosis

Hepatitis B Virus - Hepatitis B recurrence after liver transplantation is preventable

Hepatitis C Virus - Findings advance knowledge in hepatitis C virus research

Hepatitis C Virus - HCV subgenomic replicons are associated with carcinoma cell proteome alteration

Hepatitis C Virus - Studies add new findings to hepatitis C virus body of knowledge

Hepatitis Delta Virus - ADAR 1 enhances hepatitis delta virus RNA editing in interferon-alpha-stimulated host cells

Hepatitis Therapy - HCV combination therapy causes ribavirin levels and hemoglobin to decline

Hepatocellular Cancer - Findings describe new data in hepatocellular cancer research

Hepatocellular Cancer - Research add new data to hepatocellular cancer body of knowledge

Hepatocellular Cancer - Researchers' work adds to hepatocellular cancer body of knowledge

Hepatocellular Carcinoma - Hepatocellular carcinoma could be caused by iron overload

Hepatocellular Carcinoma - Hepatocellular carcinoma development is associated with serum proteome changes

Hepatocellular Carcinoma - Hepatocellular carcinoma proliferation and invasion is inhibited by ZD6474

Hepatocellular Carcinoma - Hepatocellular carcinoma proteomes can be analyzed by laser capture microdissection

Imaging - Pentax and Optiscan Imaging begin overseas sales of confocal endomicroscopy system

Imaging - Researchers' findings advance imaging research

Liver Cancer - Cholangiocellular carcinoma clinicopathology is not linked to angiogenesis factors

Liver Cancer - Researchers report details of new studies and findings in the area of liver cancer

Liver Diseases - Chronic inflammatory liver diseases involve the expression of epithelial cellular adhesion molecule

Liver Fibrosis - Liver fibrosis requires tumor necrosis factor alpha signaling

Liver Injury - Hepatic stenosis is unreliably indicated by blood oxidative stress markers

Liver Injury - Liver injury involves hydroxylation and cytochrome content

Medical Devices - Barrx Medical launches minimally invasive tool to treat Barrett esophagus

Medical Devices - HepaLife accelerates research activities and bolsters management, research teams

Obesity Pathogenesis - Nonalcoholic hepatic steatosis development is likely linked to dietary fat ingestion

Obesity Therapy - Gastric bypass 1-year outcomes for obese youth indicate health benefits offset risks

Oncology - Reports describe recent advances in oncology research

Oncology - Researchers' work adds to oncology body of knowledge

Pancreatic Cancer - Different gene expression profiles are displayed by radioresistant pancreatic cancer cell lines

Patents - Phenex AG obtains four patents relevant for its drug discovery efforts

Personnel - Exagen Diagnostics names Dr. Thomas Williams chief science officer

Personnel - Peter Licari, PhD, and Pieter Timmermans, PhD, named to Kosan's executive management team

Personnel - Thomas Gerson appointed to HistoRx management team as CFO, VP of business operations

Pharmaceutical Research - Phase III drugs slated to add additional $30 billion in revenues by 2010

Physiology - Intestinal alkaline phosphatase is associated with ABO and secretor blood group types

Product Licensing - Braintree Laboratories in-licenses rights to chemoprevention agent against colorectal cancer

Rectal Cancer - Outcome after curative resection for locally recurrent rectal cancer discussed

Respiratory Medicine - Nearly half of asthma-related ED visits made by intermittent asthma patients, study shows

Squamous Cell Carcinoma - Selecting patients in need of locoregional control of squamous cell carcinoma discussed

Stem Cell Research - Human hepatocytes repopulate the liver in a chimeric mouse model

Stem Cell Research - Pancreas early phase development regulated by endothelial-mesenchymal relay pathway

Transplant Medicine - Researchers' work adds to transplant medicine body of knowledge

Transplant Medicine - Studies advance knowledge in transplant medicine research

Transplant Medicine - Warm ischemia-reperfusion injury is decreased by tacrolimus in steatotic rat liver

Transplantation Biology - Liver transplantation outcome is aided by hepatitis B immunization

Transplantation Biology - Post-liver transplant hepatitis C recurrence and severity is influenced by polymorphisms

Transplantation Biology - Post-liver transplantation rejection is indicated by C4d

Transplantation Biology - Post-liver transplantation virus reinfection can be delayed by early therapy

Vector Development - Recombinant vectors enable the transduction of pancreatic and colon carcinoma

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