Hepatitis C Virus
Hepatitis C virus affects the expression of transferrin receptor 2
Published in Gastroenterology Week, April 10th, 2006
"Iron deposition in the liver is a common finding in patients with chronic hepatitis C (CH-C). The mechanism of this hepatic accumulation of iron is not completely understood.
"This study assessed if the protein expression of transferrin receptor 2 (TfR2) is upregulated in the liver of patients with CH-C and if TfR2 protein mediates iron accumulation during hepatitis C virus (HCV) infection," wrote R. Mifuji and colleagues, Mie University. "Liver specimens from patients with CH-C that underwent interferon (IFN) therapy (n=23) and from...
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