Gastroenterology Week

Cryptosporidiosis -  Cryptosporidium-related diarrhea and enteritis effectively treated by nitazoxanide

Gastric Cancer - Gastric carcinoma susceptibility associated with severe atrophic gastritis

Obesity Therapy - Open gastric surgery carried out in community setting shows low mortality and morbidity rates

Pancreatic Cancer - Pancreatic cancer inhibition partially results from down-regulation of Notch-1

Adverse Drug Reaction - The example of rofecoxib indicates need for thorough assessment of benefit-harm ratio

Apoptosis - Induced apoptosis protection of INS-1 cells conferred by mitochondria targeting

Artificial Liver - HepaLife's artificial liver cell research passes critical human plasma milestone

Business Update - DOR BioPharma granted SME status by the European Commission and the EMEA

Business Update - Simulations Plus releases upgrade of simulation, modeling software drug discovery

Campylobacter Outbreaks - Long-lasting gastroenteritis outbreak associated with Campylobacter milk contamination

Cancer Gene Therapy - Tumor-specific apoptotic gene targeting overcomes radiation resistance in esophageal adenocarcinoma

Cancer Research - Reports from Japan, Germany and the United States advance knowledge in cancer research

Cancer Research - Studies from Netherlands, United States and Germany describe new findings in cancer research

Cancer Therapy - Choice of chemotherapy for liver metastasis may impact surgical outcomes

Cancer Therapy - Circulating endothelial and progenitor cells may function as biomarkers for antiangiogenic therapy

Cancer Therapy - Esophageal cancer chemoradiotherapy outcome predicted by microvessel analysis

Cancer Therapy - Luteolin inhibits HepG2 cell invasion

Cancer Therapy - Symposium held in U.S. to discuss research on liver-directed radiotherapy with microspheres

Cholangiocarcinoma - Combined hepatocellular and cholangiocarcinoma described

Cholera - Cholera toxin A1(3) subdomain is required for full toxic activity

Cholera Transmission - Cholera stool bacteria repress chemotaxis to enhance transmission

Cirrhosis - Researchers from Italy, the United States and Poland publish new studies and findings in the area of cirrhosis

Clinical Trials - Researchers present Correction of Hemoglobin and Outcomes in Renal Insufficiency study data

Clinical Trials - SuperGen announces interim results of rubitecan combination trial in pancreatic cancer

Collaborations - Akorn, Natco Pharma sign a supply, margin sharing agreement

Collaborations - Dade Behring grants rights to American Diagnostica for use of factor VII-activating protease

Colon Cancer - Almost one third of colon cancer patients stop chemotherapy, rendering treatment ineffective

Colon Cancer - Chugai files innovative cancer medicine Avastin for fast approval in Japan

Colon Cancer - Colon cancer prospective randomized clinical trials reviewed

Colon Cancer - Colon cancer risk inversely associated with increased physical activity

Colon Cancer - Colonic neoplastic risk correlated poorly with clinical impression

Colon Cancer - Reports from Israel, the United States and Finland add new data to colon cancer research

Colon Cancer Therapy - Nonsteroidal anti-inflammatory drugs may have useful role in HNPCC chemoprevention

Colorectal Cancer - Colorectal cancer can be treated by either laparoscopic or open surgery

Colorectal Cancer - Colorectal cancer guidelines were followed with mixed adherence in the Southern Netherlands in 2002

Colorectal Cancer - Colorectal cancer is associated with germline mutations of the MUTYH gene

Colorectal Cancer - Colorectal cancer patients' expectations of colorectal surgery surveyed

Colorectal Cancer - Colorectal cancer prognosis linked to nuclear accumulation of beta-catenin

Colorectal Cancer - Colorectal cancer screening advised for persons with familial risk and age 40-50 years

Colorectal Cancer - Colorectal cancer staging improved by intra-operative ultrasonography

Colorectal Cancer - Colorectal carcinoma cell activities blocked via activator protein-1 inhibition

Colorectal Cancer - Risk factors for ulcerative colitis-associated colorectal cancer delineated

Colorectal Cancer - Small colorectal adenomas harbor clinically important histology

Colorectal Cancer - Sporadic colorectal cancer involves genomic instability and angiogenic growth factors

Colorectal Cancer - Studies from Argentina, Greece and Switzerland add new findings to colorectal cancer body of knowledge

Colorectal Carcinoma - Colorectal carcinoma in-vivo vs ex-vivo sentinel node mapping compared

Colorectal Carcinoma - Colorectal carcinoma patient quality of survival after chemotherapy and surgery analyzed

DNA Research - Gene silencing mimics human SPINK1 pancreatic phenotype

Diabetes - Findings from Ireland, Denmark and France describe new data in diabetes research

Diabetes - Findings from Sweden, Japan and Finland advance knowledge in diabetes research

Diabetes - New findings from Canada and the United States in the area of diabetes described

Diabetes - Recent findings in diabetes described by researchers from Germany, Norway and Japan

Diabetes - Reports from Japan, the United Kingdom and Sweden add new data to diabetes research

Diabetes - Researchers' findings from Canada and the United States advance diabetes research

Diabetes & Liver Cancer - Liver cancer risk increases among men with diabetes mellitus

Diabetes Models - Insulin responses as markers of pancreatic beta-cell mass require studies with BMI ranges

Diabetes Pathogenesis - Diabetes decreases sensitivity of rabbit renal artery to endothelin-1

Diabetes Pathogenesis - Epinephrine inhibits glucose-stimulated activation of ERK1/2 in pancreatic beta-cells

Diabetes Pathogenesis - NF-kappaB blockade protects pancreatic beta cells from diabetogenic agents

Diabetes Pathogenesis - Reduction of lysophospholipid absorption directly contributes to postprandial hyperglycemia

Diabetes Therapy - Farnesoid X receptor activation improves lipid metabolism in combined hyperlipidemic hamsters

Diabetes Therapy - Intensive insulin therapy benefit in critical illness is mainly in normoglycemia maintenance

Diabetes Therapy - K⁺ current blockers in pancreatic beta-cells enhance glucose-dependent insulin secretion

Diabetes Therapy - Pancreas versus islet transplantation in diabetes mellitus compared

Diagnostics -  Cryptosporidium parasites rapidly detected in environmental samples by real-time PCR

Diagnostics - New findings from Switzerland, the United States and Germany in the area of diagnostics detailed

Diagnostics - Researchers' data from Japan, Netherlands and Italy advance diagnostics research

Diagnostics - Studies from South Korea, Belgium and Japan describe new findings in diagnostics research

Diet & Nutrition - Gastric and esophageal adenocarcinoma risk linked to meat intake

Drug Development - E.U. label change for INTRON A incorporates long-term efficacy data in chronic hepatitis C

Drug Development - Lentinan stimulates innate and adaptive immunity against Listeria monocytogenes infection

Drug Development - U.S. FDA grants Orphan Drug designation to Nexavar for treatment of liver cancer

Drug Safety - Spironolactone can be used with an acceptable side-effect profile as long as patients are monitored

Embryonic Stem Cell Research - Embryonic stem cell LRH-1 expression directed by mlrh-1 variant and promoter

Endocrinology - AICAR and metformin inhibit hepatic glucose phosphorylation by AMPK-independent pathway

Endocrinology - Genistein stimulates insulin secretion in pancreatic beta-cells by cAMP-dependent PKA path

Enterotoxigenic Escherichia Coli Vaccine - Reduced doses of oral-killed ETEC plus cholera toxin B subunit vaccine safe and immunogenic

Epidemiology - Human and animal enteric caliciviruses detected in oysters from various U.S. coastal areas

Escherichia Coli - Enterotoxigenic Escherichia coli two-partner secretion locus identified

Escherichia Coli Outbreaks - Human Vero cytotoxigenic Escherichia coli O157 infection linked to birds

Esophageal Cancer - Findings from the United States and Japan describe new data in esophageal cancer research

Esophageal Cancer - Reports from Japan and Germany describe recent advances in esophageal cancer research

Esophageal Squamous Cell Carcinoma - Esophageal squamous cell carcinoma survival not affected by esophagectomy errors

Esophageal Squamous Cell Carcinoma - Esophageal squamous cell carcinoma treated by docetaxel and heavy carbon-ion beam irradiation

Finance - Exact Sciences announces total revenues of $1.2 million for first quarter