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Cancer Therapy
Micro-RNA is involved in cholangiocarcinoma chemotherapy response
August 7th, 2006
According to recently published research from the United States, micro-RNA (miRNA) is involved in growth and response to chemotherapy in human cholangiocarcinoma cell lines. "miRNA are endogenous regulatory RNA molecules that modulate gene expression. Alterations in miRNA expression can contribute to tumor growth by modulating the functional expression of critical genes involved in tumor cell proliferation or survival," wrote F.Y. Meng and colleagues, Texas A&M University. "Our aims were to identify specific miRNA involved in the regulation of cholangiocarcinoma growth and response to chemotherapy. miRNA expression in malignant and nonmalignant human...
Source: Gastroenterology Week (2006-08-07)
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