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Colorectal Cancer
Colorectal cancer proliferation, invasion, and metastasis are advanced by trypsin
August 7th, 2006
Colorectal cancer proliferation, invasion, and metastasis are advanced by trypsin. "Trypsin is involved in colorectal carcinogenesis and promotes proliferation, invasion, and metastasis. Although a well-known pancreatic digestive enzyme, trypsin has also been found in other tissues and various cancers, most importantly of the colorectum," scientists in Norway report. "Moreover," said K. Soreide and colleagues, Stavanger University Hospital, "colorectal cancers with trypsin expression have a poor prognosis and shorter disease-free survival. Biological understanding of how trypsin causes cancer progression is emerging. It seems to act both directly and...
Source: Gastroenterology Week (2006-08-07)
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