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Cytomegalovirus & Lymphoma
Cytomegalovirus infection triggers lymphoma cell apoptosis in the liver
August 7th, 2006
Cytomegalovirus infection triggers lymphoma cell apoptosis in the liver. "Cytomegalovirus (CMV) poses a threat to the therapy of hematopoietic malignancies by hematopoietic stem cell transplantation, but efficient reconstitution of antiviral immunity prevents CMV organ disease. Tumor relapse originating from a minimal residual leukemia poses another threat. "Although a combination of risk factors was supposed to enhance the incidence and severity of transplantation-associated disease, a murine model of a liver-adapted B-cell lymphoma has previously shown a survival benefit and tumor growth inhibition by nonlethal subcutaneous infection with murine...
Source: Gastroenterology Week (2006-08-07)
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