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Gastroenterology Week

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Drug Development



Procter & Gamble and ARYx investigate treatment for gastrointestinal disorders



August 7th, 2006

Procter & Gamble Pharmaceuticals, Inc., a division of The Procter & Gamble Company (PG) and ARYx Therapeutics announced a strategic alliance under which P&G will develop and commercialize ARYx's novel drug, ATI-7505, for the treatment of gastrointestinal disorders such as gastroesophageal reflux disease (GERD) and gastroparesis.

ATI-7505 is an oral, serotonin type 4 (5HT4) agonist that is in Phase

development. It has been shown to have prokinetic properties (increases upper GI motility, which is believed to play a beneficial role in GI symptom reduction). Based on its mechanism of action, initial studies show that ATI- 7505 prevents the regurgitation...


Source: Gastroenterology Week (2006-08-07)

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