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Gastric Cancer
Gastric cancer risk linked to cyclooxygenase-2 polymorphisms in a Chinese population
August 7th, 2006
The risk of developing gastric cancer (GC) was linked to genetic variants in cyclooxygenase-2 (COX-2) in a Chinese population. Researchers in the People's Republic of China conducted a study "to screen the genetic variants in COX-2, and evaluate their effects on COX-2 expression and risk of GC and its precursors, a population-based study was conducted in Linqu County, Shangdong Province, an area of China, a high-risk area of GC. Genotypes were determined by polymerase chain reaction (PCR)-based denaturing high-performance liquid chromatography analysis in 248 GC cases and 1523 subjects with precancerous gastric lesions. COX-2 expression was detected by...
Source: Gastroenterology Week (2006-08-07)
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