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Gastroenterology
Chronic anal fissure 'chemical sphincterotomy' treatment is not definitive
August 7th, 2006
Pharmacologic anal sphincter relaxants are not a definitive treatment for many patients. "Pharmacologic anal sphincter relaxants promote fissure healing; however, their effect is transient and the risk of late recurrence remains uncertain. From August 1997 to August 2002, patients with chronic anal fissure attending our outpatient clinic were treated with a protocol that included: topical isosorbide dinitrate, 2.5 mg, or nifedipine, 0.2% t.i.d., or the combination of both," scientists writing in the journal Diseases of the Colon & Rectum report. "Botulinum toxin 20 units was injected to the internal anal sphincter to those who failed. All the...
Source: Gastroenterology Week (2006-08-07)
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