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Cholangiocarcinoma

Cholangiocarcinoma not independently prognosticated by P53 protein expression

Published in Gastroenterology Week, November 6th, 2006

Cholangiocarcinoma could not be independently prognosticated by P53 protein expression.

According to a recent article published in the World Journal of Gastroenterology, scientists in the People's Republic of China conducted a study "to characterize the tumor suppressor gene p53 mutations and study the correlation of p53 gene mutation and the expression of P53 protein in cholangiocarcinoma. A total of 36 unselected, frozen samples of cholangiocarcinoma were collected. p53 gene status(exon 5-8) and P53 protein were examined by automated sequencing and immunohistochemical staining, combined with the clinical parameters of patients."

"p53 gene...

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