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Angiotensins

Scientists at Kyungpook National University target angiotensins

Published in Gastroenterology Week, February 5th, 2007

Research findings, "Increased AQP2 targeting in primary cultured IMCD cells in response to angiotensin II through AT1 receptor," are discussed in a new report. According to recent research from Korea, "Vasopressin and angiotensin II (ANG II) play a major role in renal water and Na(+) reabsorption. We previously demonstrated that ANG II AT(1) receptor blockade decreases dDAVP-induced water reabsorption and AQP2 levels in rats, suggesting cross talk between these two peptide hormones (Am J Physiol Renal Physiol 288: F673-F684, 2005)."

"To directly address this issue, primary cultured inner medullary collecting duct (IMCD) cells from male Sprague-Dawley rats were treated...

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