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Adenoma

Research from the United Kingdom and United States in adenoma provides new insights

Published in Gastroenterology Week, February 5th, 2007

Reports from the United Kingdom and United States highlight recent research in adenoma.

Study 1: A report, "Genetic variants of UGT1A6 influence risk of colorectal adenoma recurrence," is newly published data in Clinical Cancer Research. According to recent research from Nottingham, the United Kingdom, "The UDP glucuronosyltransferase 1A6 (UGT1A6) and cytochrome P450 2C9 (CYP2C9) enzymes participate in the metabolism of nonsteroidal anti-inflammatory drugs, endogenous substances, and carcinogens. Functional polymorphisms of UGT1A6 (T181A and R184S) and CYP2C9 (R144C and I359L) have been reported to modify the protective effect of aspirin on colorectal adenoma...

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