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Angiotensins

Research on angiotensins discussed by scientists at University of Arizona, Arizona Health Sciences Center

Published in Gastroenterology Week, February 19th, 2007

Scientists discuss in "The role of angiotensin II in stress urinary incontinence: A rat model" new findings in angiotensins. According to recent research published in the journal Neurourology and Urodynamics, "Pharmacological treatment for stress urinary incontinence (SUI) is limited to the use of non-selective alpha-agonists, which are often ineffective. Non-adrenergic mechanisms have also been implicated in urethral closure, including angiotensin II (Ang-II), which has been demonstrated throughout the urinary tract."

"We investigate the role of Ang-II in urethral tone in a rat model of SUI. Abdominal leak point pressure (ALPP) and retrograde urethral pressure...

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