Breast Cancer
Ovarian cancer may mimic fallopian tube formation
Published in Gastroenterology Week, March 19th, 2007
A new study suggests that ovarian cancer cells form by hijacking a developmental genetic process normally used to form fallopian tubes. Scientists at the Georgia Institute of Technology and the Ovarian Cancer Institute discovered that the protein, PAX8, is involved in the development of fallopian tubes and is present in ovarian cancer cells, but not in normal ovarian tissue. The discovery not only provides a new target for diagnostic and therapeutic interventions, but also opens new avenues for basic research in ovarian cancer pathology. The research appears in Volume 104, Issue 3 of the journal Gynceologic Oncology.
"Our finding sustains the promise of a molecular...
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