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Hepatitis A Virus Immunology

Research from University of Cincinnati, Division of Digestive Diseases provides new data about hepatitis A virus immunology

Published in Gastroenterology Week, December 24th, 2007

A new study, 'Characterization of hepatitis E-specific cell-mediated immune response using IFN-gamma ELISPOT assay,' is now available. According to a study from the United States, "In developing countries, hepatitis E (HEV) and hepatitis A (HAV) are the major causes of acute viral hepatitis with similar feco-oral modes of transmission. In contrast to the high seroprevalence of hepatitis A infection, a low seroprevalence of HEV among children in endemic areas has been reported."

"These data suggest the possibility that silent HEV infection is undiagnosed by the current available methods. Many of the serological tests used for HEV diagnosis have poor specificity and are...

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