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Adrenoleukodystrophy

Research from Medical University of Vienna, Institute of Neurology in the area of adrenoleukodystrophy published

Published in Gastroenterology Week, December 24th, 2007

Scientists discuss in 'Distribution and cellular localization of adrenoleukodystrophy protein in human tissues: implications for X-linked adrenoleukodystrophy' new findings in adrenoleukodystrophy. "Defects of adrenoleukodystrophy protein (ALDP) lead to X-linked adrenoleukodystrophy (X-ALD), a disorder mainly affecting the nervous system white matter and the adrenal cortex. In the present study, we examine the expression of ALDP in various human tissues and cell lines by multiple-tissue RNA expression array analysis, Western blot analysis, and immunohistochemistry," scientists in Vienna, Austria report.

"ALDP-encoding mRNA is most abundant in tissues with high energy...

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