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Obesity and Diabetes Cell Biology

Research on obesity and diabetes cell biology discussed by scientists at University of Wisconsin, Department of Biochemistry

Published in Gastroenterology Week, June 9th, 2008

Researchers detail in 'A gene expression network model of type 2 diabetes links cell cycle regulation in islets with diabetes susceptibility,' new data in obesity and diabetes. According to a study from the United States, "Insulin resistance is necessary but not sufficient for the development of type 2 diabetes. Diabetes results when pancreatic beta-cells fail to compensate for insulin resistance by increasing insulin production through an expansion of beta-cell mass or increased insulin secretion."

"Communication between insulin target tissues and beta-cells may initiate this compensatory response. Correlated changes in gene expression between tissues can provide...

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