Gene Therapy
New gene therapy study findings reported from Sojo University
Published in Gastroenterology Week, November 24th, 2008
Fresh data on gene therapy are presented in the report 'ADBP-1 regulates an ADAR RNA-editing enzyme to antagonize RNA-interference-mediated gene silencing in Caenorhabditis elegans.' According to recent research published in the journal Genetics, "Small interfering RNAs (siRNAs) and microRNAs (miRNAs) mediate gene silencing through evolutionarily conserved pathways. In Caenorhabditis elegans, the siRNA/miRNA pathways are also known to affect transgene expression."
"To identify genes that regulate the efficiencies of the siRNA/miRNA pathways, we used the expression level of a transgene as an indicator of gene silencing and isolated a transgene-silencing...
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