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University Hospital Heidelberg

Toxic bile damages the liver

Published in Gastroenterology Week, November 24th, 2008

Researchers at the Heidelberg University Hospital have discovered a new genetic disease that can lead to severe liver damage. Because a protective component of the bile is missing, the liver cells are exposed to the toxic components of the bile, resulting in cirrhosis of liver, a transformation of liver cells into connective tissue with a gradual loss of liver function. This could explain some of the cases of liver cirrhosis of unknown origin and open up a new approach for treatment. The research has now been published in the journal "Hepatology".

Some of the known frequent causes of cirrhosis of the liver are liver inflammation due to a virus, alcohol abuse, autoimmune...

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