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American Society of Nephrology

High phosphorus linked to coronary calcification in chronic kidney disease

Published in Gastroenterology Week, December 22nd, 2008

For patients with moderate chronic kidney disease (CKD), higher levels of phosphorus in the blood are associated with increased calcification of the major arteries and heart valves—which may contribute to the increased risk of cardiovascular disease in patients with CKD, reports a study in the Journal of the American Society of Nephrology (JASN).

"Previous studies have found that a very high level of phosphorus in the blood can lead to cardiovascular disease and vascular calcification in dialysis patients," comments Bryan Kestenbaum, MD, of the University of Washington in Seattle, Washington, one of the authors of the new study. "We are now recognizing that even a mild...

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