Fibrosis

New fibrosis study findings recently were reported by F.Y. Ma and co-researchers

Published in Gastroenterology Week, March 2nd, 2009

According to recent research from Clayton, Australia, "Ma FY, Liu J, Kitching AR, Manthey CL, Nikolic-Paterson DJ. Targeting renal macrophage accumulation via c-fms kinase reduces tubular apoptosis but fails to modify progressive fibrosis in the obstructed rat kidney."

"Am J Physiol Renal Physiol 296: F177-F185, 2009. First published November 15, 2008; doi: 10.1152/ajprenal.90498.2008.-The role of macrophages in promoting interstitial fibrosis in the obstructed kidney is controversial. Macrophage depletion studies in the unilateral ureter obstruction (UUO) model have produced opposing results, presumably reflecting the subtleties of the individual depletion methods...

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Source: Gastroenterology Week (2009-03-02)

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