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Nephrology

Research from University of Western Ontario in the area of nephrology published

Published in Gastroenterology Week, March 2nd, 2009

"Unlike creatinine, Cystatin C (CysC) is believed to be independent of body composition in both adults and children. Recent findings in adults, suggesting an improved performance of CysC-based estimated glomerular filtration rate (CysC eGFR) by accounting for body mass, necessitated a careful re-evaluation of this issue in children," scientists in London, Canada report.

"We studied 240 children (median age 11.7 years, range 2-17.9 years, 107 girls), with various kidney diseases, for any change in the relationship between Tc-99 DTPA GFR and CysC eGFR after accounting for body mass. For body mass assessment, body mass index (BMI) z-score was calculated using...

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