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Gastroenterology

New gastroenterology research from Children's Hospital, Division of Infectious Diseases described

Published in Gastroenterology Week, March 30th, 2009

Research findings, 'Genetic analysis of Drosophila melanogaster susceptibility to intestinal Vibrio cholerae infection,' are discussed in a new report. According to recent research from the United States, "We previously demonstrated that Vibrio cholerae is able to colonize the intestine of the fly to produce a lethal infection. Here we present the results of a genetic screen undertaken to identify factors that alter susceptibility of the fly to intestinal V. cholerae infection."

"In this model of infection, the Eiger/Wengen signalling pathway protects the fly against infection. Furthermore, mutations within the IMD signalling pathway increase resistance to...

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