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Adenoma

Studies from M.W. Musch and co-authors have provided new information about adenoma

Published in Gastroenterology Week, March 30th, 2009

"Musch MW, Arvans DL, Wu GD, Chang EB. Functional coupling of the downregulated in adenoma Cl-/base exchanger DRA and the apical Na+/H+ exchangers NHE2 and NHE3," researchers in the United States report.

"Am J Physiol Gastrointest Liver Physiol 296: G202-G210, 2009. First published December 4, 2008; doi:10.1152/ajpgi.90350.2008.-Non-nutrient-dependent salt absorption across the brush-border membrane of intestinal epithelial cells is primarily mediated by coupled apical Na+/H+ (aNHE) and anion exchange transport, with the latter suspected of being mediated by DRA (downregulated in adenoma; SLC26A3) that is defective in congenital chloridorrhea. To investigate DRA in...

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