Enzyme Research

Studies from T. Reiner and co-researchers in the area of prostate cancer published

Published in Gastroenterology Week, May 25th, 2009

According to a study from the United States, "Clinical trials have shown that chemotherapy with docetaxel (Doc) combined with prednisone can improve survival of patients with androgen-independent prostate cancer (AI-PC). It is likely that the combination of Doc with other novel agents would also improve the Survival of AI-PC patients."

"We investigated whether the combination of Doc and 2-methoxyestradiol (2ME2), an endogenous metabolite of estradiol promising for cancer therapy, can increase apoptotic cell death in prostate cancer cells. Low concentration 2ME2 (0.5-1 mc M) + Doc (0.05-0.1 nM) combinations inhibit cell growth, increase G2/M cell cycle arrest, and...

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Source: Gastroenterology Week (2009-05-25)

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