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Yellow Fever

Research data from Cornell University, Medical Department update understanding of yellow fever

Published in Gastroenterology Week, May 25th, 2009

"Piermarini PM, Weihrauch D, Meyer H, Huss M, Beyenbach KW. NHE8 is an intracellular cation/H+ exchanger in renal tubules of the yellow fever mosquito Aedes aegypti," investigators in the United States report.

"Am J Physiol Renal Physiol 296: F730-F750, 2009. First published February 4, 2009; doi:10.1152/ajprenal.90564.2008.-The goal of this study was to identify and characterize the hypothesized apical cation/H+ exchanger responsible for K+ and/or Na+ secretion in the renal (Malpighian) tubules of the yellow fever mosquito Aedes aegypti. From Aedes Malpighian tubules, we cloned ''AeNHE8,'' a full-length cDNA encoding an ortholog of mammalian Na+/H+ exchanger 8 (NHE8)....

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