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University of Innsbruck

Why the thumb of the right hand is on the left hand side

Published in Gastroenterology Week, June 8th, 2009

This press release is available in German. It is the concentration of a few signaling molecules that determines the fate of individual cells during the early development of organisms. In the renowned journal Current Biology, a team of molecular biologists led by Pia Aanstad of the University of Innsbruck reports that a variety of molecular mechanisms accounts for the interpretation of the concentration of the signaling molecule Hedgehog.

The development of an organism is a complex process to which a dozen or hundreds of signaling molecules contribute. Some of these molecules have dozens of functions in the fruit fly and in humans alike. One of these molecules – Hedgehog...

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